Talk-Polywell.org

Nutritional omega-3 deficiency <snip>

Finally, the dietary-induced reduction of CB(1)R functions in mood-controlling structures was associated with impaired emotional behavior. These findings identify a plausible synaptic substrate for the behavioral alterations caused by the n-3 PUFAs deficiency that is often observed in western diets.

http://www.ncbi.nlm.nih.gov/pubmed/21278728

Granny’s translation – “The US diet sucks big time and we are fat, undernourished, and crazy because of it. We get WAY too much Omega 6 and not enough Omega 3. Not getting enough Omega 3 can make you crazy because without it, the CB1 cannabinoid receptors in your brain aren’t made right- a chunk that is supposed to be attached, isn’t! Broken receptors give you “impaired emotional behavior”. So we think it’s the low Omega 3 diet is making the US totally nuts!”

Now, since the CB1 receptors are not working right because of that broken piece, does this also mean that people who have been deficient in Omega 3 for a while are missing out on the full medical benefits- and their maximum high?

The two most popular forms of Omega 3 supplements are fish oils and flax seed oil. Fish oil may be contaminated with mercury- so many people prefer flax seed oil. Flax is fine, but has a few minor problems nutritionally- look it up if you are curious.

But there is another plant oil that is an even better source of Omega 3 than flax seed oil……….hemp seed oil! (3) The very thing we need to make our CB receptors work at their best is in the hemp plant! Cannabis is the source of the cannabinoids that we need to heal ourselves and the source of the Omega 3 we need for our receptors to do their jobs properly!

http://www.jackherer.com/archives/grann ... onnection/

Some clinical studies[43][52][53] indicate that the ingested ratio of omega−6 to omega−3 (especially linoleic vs alpha-linolenic) fatty acids is important to maintaining cardiovascular health. However, two studies published in 2005 and 2007 found that while omega−3 polyunsaturated fatty acids are extremely beneficial in preventing heart disease in humans, the levels of omega−6 polyunsaturated fatty acids (and therefore the ratios) were insignificant.[54][55]

<snip>

Typical Western diets provide ratios of between 10:1 and 30:1 (i.e., dramatically higher levels of omega−6 than omega-3).[63] The ratios of omega−6 to omega−3 fatty acids in some common vegetable oils are: canola 2:1, hemp 2-3:1,[64] soybean 7:1, olive 3–13:1, sunflower (no omega−3), flax 1:3,[65] cottonseed (almost no omega−3), peanut (no omega−3), grapeseed oil (almost no omega−3) and corn oil 46:1 ratio of omega−6 to omega−3.[66]

http://en.wikipedia.org/wiki/Omega-3_fatty_acid

There are two main endocannabinoids which help regulate your system. Those two EC are: N-arachidonoylethanolamine and 2-Arachidonoylglycerol. Both are made from Arachidonic acids, which are found in the membrane structure.

They are released through an enzyme reaction, which breaks them down and releases them into the blood.

Since Arachidonic acid comes from the omega-6 family, naturally you will find altered omega-6/omega-3 ratio. This increases inflammation, which is exactly what you want to avoid.

Here comes Krill to the rescue!

Essential fatty acids found in krill are released into the blood, resulting in a positive omega-3 to omega-6 ratio. This promotes regulation of the endocannabinoid system and reduces inflammation in the body.

What else does Krill oil do?

Research done by Batteta et al. determined that supplementation with Krill oil results in a decrease of EC levels around organs. The researchers found Krill oil changes AEA and 2-AG found in visceral adipose tissue, or the bad fat, which surrounds organs. They found that AEA and 2-AG were significantly decreased by use of Krill oil supplementation.

The significance of lowered EC in visceral tissue also decreases triglycerides.

They found that Krill oil decreased triglyceride levels in both the heart and the liver. They also saw lower LDL cholesterol and a decreased expression of TNF-α in the body.

TNF-α is a cytokine released from adipose tissue which causes inflammation, and can lead to other metabolic conditions.

A dysfunction in the EC system can increase the ratio between omega-6 to omega-3 fatty acids. Having increased triglyceride levels in the heart and liver increases your risk factors for disease.

http://www.getprograde.com/krill-oil-an ... ystem.html