I'm not sure what the basis for argument is here. The conditions and consequences have been hashed out here, and is referenced in many texts. The fusion crosection curves are well accepted . D=T peaks around ~ 60-70 KeV, then falls. there is little reason for pushing to higher energies. I have presented a curve of the DT fusion crosection vs the Coulomb collision crossection. In this case the DT fusion crossection peak corresponds to the best ratio between fusion and scattering collisions at a ratio of ~ 1:10. The Coulomb crossection falls at even higher energies, but the DT- fusion crossection nearly parallels it. No gain, and lots of penalties (bremstrulung, black body radiation,eventually atom smashing instead of fusion, etc).
The fusion crosection curves are derived from experiment, and the difference between them and the theoretical absolute Coulomb barrier math is explained as quantum uncertainty/ tunneling effects. Like much of quantum mechanics it doesn't always make sense, but it does accurately predict results.
If you are talking about DD fusion. purely from the crossection point of view it might make since to push to collision energies of a few MeV. I suspect that the fusion probabilities may actually exceed the Coulomb collision probabilities. But this ignores other losses. The energy gain per fusion goes down (more input energy), the bremsstrulung is much greater ( I believe it goes up as the 1.5 power of the temperature), and of course as chrismb stated the atom smashing effects will reach dominance at some point. This is endothermic (I think) and not only robs energy but scatters any ions as well.
I believe that at ~ 60-80KeV the fusion to Coulomb collision ratio is ~ 1/100 that of DT. (~ 1:1000 ratio). As a few hundred KeV the ratio may be similar to DT at ~ 60-80 KeV. [EDIT- not because the DD fusion crossection is increasing that much, but because the Coulomb collision crossection in continuing to decrease] , but other loss concerns will reach a optimal balance and I doubt it is much above several hundred KeV. I believe Bussard was careful in his calculation (as opposed to me

) and his quotes of ~ 80 KeV for a D-D burning Polywell was the best balance between thermalization issues, other losses, fusion rate, and technical concerns. For P-B11 this is ~ 200 KeV. Additional fusion rates vs scattering could be achieved, but with all of the +/- concerns this is the best balance.
I might add that running at ~ 2 MeV (it doesn't make any since for DT due to the shape of the crossection curve )might make since if you were trying to make nuclear reactions dominate over coulomb scattering reactions. But note that these nuclear reactions is a mix of fusion and smashing, the total exothermic energy delivered is decreasing, the input energy is increasing, the losses are increasing ( the Coulomb losses are not increasing as fast, but they are still increasing) so it is a losing game once you pass some point, which for DD is possible at several hundred KeV. - The fusion crossection graph is still going up slowly, but at a slower rate than the slopes for the losses.
If your purpose is to maximize fuaion and/ or atom smashing, irregardless of the cost then pushing to higher energies makes sence. But from a energy balance situation it does not.
In a Tokamak, where confinement times and thus losses per ion is less, for DT fusion energy balance and energy density concerns, I think that ~ 20 KeV may be the best compromise.
In a Polywell where confinement time is less and with other issues it makes sense to operate at higher levels. For DT fusion I speculate this may be more in the region of 40-50 KeV.
For systems that have very short confinement times it may make sense to push even higher (at least for DD fusion which has a unique fusion crossection curve), but again at some point you reach a maximum benefit, that MIGHT allow for net positive energy generation. This would definitely not be above the energy level where atom smashing became prevelent compared to the fusion rate.
[EDIT Oppenheimer-Phillips reaction = atom smashing]
And another point- ignoring the atom smashing componet. For DD fusion, at the temperature goes up the scattering of a beam becomes less, but even if this preserves the ions in the reaction space longer, there are other losses. The slope of the DD fusion crossection is shallow above ~ 100 KeV,. The Bremsstrulung goes up a ~ 1.5 rate , the black body radiation goes up at ? rate. If the fusion crossection goes up at a rate below ~ these rates plus the input energy rate, then it is a loss.
Using soem made up numbers. Increasing the input energy from 100 KeV to 1,000 KeV costs 10 units of power. The Bremstrulung losses costs 10^1.5 or ~ 20 units of power. Black body losses costs ~ 1 unit of power (???). Note that this ignores particle containement losses.
If the slope for the DD fusion crossection is ~ 2 over this range then the incresed fusion would be 2 * 10 or ~ 20X. Subtract the losses (~ 31 units of power). The result is a net loss of 11 units of power.
Recovering the energy from some of these losses helps, but is limited, and it penalizes the positive numbers just the seam. Assume steam conversion at 30% for the losses. Now the losses only ad up to ~ 20 units. The fusion gain is ~ 20 units, but converting it to useful power reduces the fusion output to ~ 14 U of useful power. It is still a losing proposition. This is why reactor schemes ideally operate at regions of the fusion crossection curves that are steep. The peak or maximal position on the graph is only desired if you are not concerned with energy balance or Q. There may be some compromising for technical, power density, actual particle confinement time issues, thermalization issues, etc, but there is not a lot of wiggle room.
This is why Joel Rogers used 15,000 KeV as the drive energy for his Polywell simulations a couple of years ago. This is nowhere near the optimal temperature for power density concerns, or even confinement vs fusion rate concerns, or thermalization issues, but it is the steepest part of the graph and maximizes Q at these constrained assumptions.
Dan Tibbets
To error is human... and I'm very human.