Factor X have we finally found the fountain of Youth?

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GIThruster
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Re: Factor X have we finally found the fountain of Youth?

Post by GIThruster »

Skipjack wrote:I find the whole cloning scare a non issue as well.
This is a pretty common position, but what it really entails is a lack of sympathy to understand and grapple with the concerns of others. All real bio-ethics involves a commitment to things like the necessity of public policy to give an attentive ear to all voices in the concern. You may have no troubles with people cloning people, but lots of people do, and this being the case it requires a substantial investment merely to demonstrate those making public policy have heard the voices of our democracy.

I was never swayed by the arguments against using embryos, but that is very different from saying I can't understand why people would make such arguments. This is democracy in action and though life scientists may find this inconvenient, its certainly necessary when we're talking abut the disposition of public funds. Certainly too, when we're talking about issues that may threaten the public such as genetic manipulation of biological organisms that are then released into the environment we all share, interested parties have a right to be heard.

In Mexico, the people had no say whether Monsanto should use their genetically modified corn out in the open, and the almost immediate result of this was that it over-competed against several natural strains in Mexico to the point these have nearly been wiped out. Do the residents of Mexico have a right to be heard on this issue? Certainly! Should they be able to sue Monsanto if they like? Certainly! Should they win in court? No. Monsanto cannot be held liable for the failure of natural crops to compete with its BT Corn. But note the bio-ethics debate is a process of advised consent inside democracies and is integral to what makes a healthy democracy.
"Courage is not just a virtue, but the form of every virtue at the testing point." C. S. Lewis

williatw
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Location: Ohio

Re: Factor X have we finally found the fountain of Youth?

Post by williatw »

Skipjack wrote:I find the whole cloning scare a non issue as well.
I don't think you’re fully considering the ramifications. Suppose some former Skipjack belle, unbeknownst to you took some will say "cheek" scrapings. Live cells, a little bit of work (okay allot of work)...next thing you know there are three or four (or more) little Skipjacks running around, and she hits you up for some serious child support. To say nothing of how Missus Skipjack would take the news.

Skipjack
Posts: 6818
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Re: Factor X have we finally found the fountain of Youth?

Post by Skipjack »

williatw wrote:
Skipjack wrote:I find the whole cloning scare a non issue as well.
I don't think you’re fully considering the ramifications. Suppose some former Skipjack belle, unbeknownst to you took some will say "cheek" scrapings. Live cells, a little bit of work (okay allot of work)...next thing you know there are three or four (or more) little Skipjacks running around, and she hits you up for some serious child support. To say nothing of how Missus Skipjack would take the news.
Well currently we are not in the position to do that, by a long shot. Something like that requires too much effort and staff. It would certainly be traceable. Either way, it would be easy to adapt the legislation in this regard. Besides, one would probably see the fact that they are clones by the length of the telomeres.

paperburn1
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Re: Factor X have we finally found the fountain of Youth?

Post by paperburn1 »

I remember the "DOLLY" clone experiments and the cloned sheep did not live that Much longer than the mother and she should have lived for years longer.
On 14 February 2003, Dolly was euthanised because she had a progressive lung disease and severe arthritis.[14] A Finn Dorset such as Dolly has a life expectancy of around 11 to 12 years, but Dolly lived to be only a month over 6.5 years of age. A post-mortem examination showed she had a form of lung cancer called Jaagsiekte,[15] which is a fairly common disease of sheep and is caused by the retrovirus JSRV.[16] Roslin scientists stated that they did not think there was a connection with Dolly being a clone, and that other sheep in the same flock had died of the same disease.[14] Such lung diseases are a particular danger for sheep kept indoors, and Dolly had to sleep inside for security reasons.
Some have speculated that a contributing factor to Dolly's death was that she could have been born with a genetic age of six years, the same age as the sheep from which she was cloned.[17] One basis for this idea was the finding that Dolly's telomeres were short, which is typically a result of the ageing process.[18][19] The Roslin Institute have stated that intensive health screening did not reveal any abnormalities in Dolly that could have come from advanced aging

The two problems stated are normally associated with older sheep. So i do wonder.....
I am not a nuclear physicist, but play one on the internet.

Skipjack
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Joined: Sun Sep 28, 2008 2:29 pm

Re: Factor X have we finally found the fountain of Youth?

Post by Skipjack »

Well, the length of the telomeres is part of the aging process. They get shortened with every cycle. There may be a way around it in the future (reverse telomerase or sorts), but it is still in early stages, I believe.

GIThruster
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Joined: Tue May 25, 2010 8:17 pm

Re: Factor X have we finally found the fountain of Youth?

Post by GIThruster »

That was a decade ago. I would be very surprised if someone hadn't cloned people by now. It is illegal in most countries, but just the kind of thing China or North Korea would do. They treat their people like possessions already so nothing to stop them cloning them.
"Courage is not just a virtue, but the form of every virtue at the testing point." C. S. Lewis

hanelyp
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Re: Factor X have we finally found the fountain of Youth?

Post by hanelyp »

If China or North Korea wanted more people they have a cheaper method than cloning.
The daylight is uncomfortably bright for eyes so long in the dark.

Skipjack
Posts: 6818
Joined: Sun Sep 28, 2008 2:29 pm

Re: Factor X have we finally found the fountain of Youth?

Post by Skipjack »

hanelyp wrote:If China or North Korea wanted more people they have a cheaper method than cloning.
LOL, yeah in China they would just say "go ahead! Have more than one child!". They might do genetic enhancements though in China. There is a big research project going on there right now.

williatw
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Re: Factor X have we finally found the fountain of Youth?

Post by williatw »

Google scoops up another high-profile scientist for anti-death project

Image

Above: New Calico recruit Dr. Cynthia Kenyon.
Image Credit: UCSF Kenyon Lab

Google’s secretive Project Calico is aimed at defeating death itself — or at least staving it off far longer than ever before.

To that end, the company has been recruiting some of the top names in anti-aging and genetics research. The latest is Cynthia Kenyon, a high-profile biochemist and biophysicist at the University of California, San Francisco, according to a report in the San Francisco Chronicle.

VentureBeat actually reported in November that Kenyon would be joining Calico; she has served as a consultant to the project since then. The Chronicle confirmed that she has finally left her UCSF post to join Calico full time, although she’ll retain the title of professor emeritus at UCSF.

Kenyon’s UCSF lab has focused its research since the 1990s on a small roundworm, C. elegans. Kenyon’s team found that modifications to a gene called daf-2 resulted in doubling the lifespan of the worms, from two weeks to four; another gene, daf-16, kept them youthful despite their extended ages.

“Seeing them is like being with someone that looks 40 and learning that they are really 80,” the lab notes on its website.

Subsequent research, by other scientists, have shown that similar genes control lifespan and aging in fruit flies, mice, and possibly even humans. Changing the genes slows aging and increases resistance to age-related diseases such as cancer, heart failure, and protein-aggregation disease.

In coming to Calico, Kenyon joins former Genentech chief executive and current Calico CEO Arthur Levinson; former Roche chief medical officer Hal Barron; Robert Cohen, a senior oncologist at Genentech; and David Botstein, the former director of the Lewis-Sigler Institute for Integrative Genomics at Princeton University.

It’s an A-team of genetics researchers that reflects the magnetism that Google’s powerful vision (and cash) exerts. Whether the team will be able to accomplish things where others have failed is still uncertain. Few details on what exactly Calico is doing have emerged, apart from Google founder Larry Page’s initial post on the project and Levinson’s bland “it’s great to be part of the team” note from September.

In December, VentureBeat called Calico “the most interesting startup in Silicon Valley.”




http://venturebeat.com/2014/04/20/googl ... h-project/
Last edited by williatw on Fri Mar 06, 2015 8:59 pm, edited 1 time in total.

williatw
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Location: Ohio

Re: Factor X have we finally found the fountain of Youth?

Post by williatw »

Scientists at Johns Hopkins Come Closer to Eliminating Heart Disease

A world without heart disease seems impossible. But researchers at Johns Hopkins just got one step closer.


Image

Scientists at Johns Hopkins University may be one step closer to eradicating debilitating heart diseases in humans, particularly those caused by excessive buildup of cholesterol.


A new study published in the journal Circulation shows that a synthesized drug reduces, and may even eradicate, the effects of high-fat and high-cholesterol diets. And though the drug is prosperous for the heart and brain most specifically, the entire body may benefit from this development.


“It’s the entire cardiovascular system that’s affected,” Ekaterina Pesheva, a representative for Johns Hopkins, told The Daily Beast. “The reason we’re worried about the heart and the brain is because those are the centers that end up being the most debilitating to human life when affected by fatty buildups.”

The study shows that the new drug under examination, known now as D-PDMP, changes the way fat metabolism works, and eliminates the risk of heart attack and heart disease. The drug halts the development of atherosclerosis, a word referring to the hardening of the arteries. Atherosclerosis is based on a buildup of fat and cholesterol in blood vessels, and happens to be the main cause of heart attacks in humans. Most notably, atherosclerosis is the No. 1 cause of death in humans (perhaps a little-known fact in a world rampant with famine, war, and crime
Perhaps the most remarkable aspect of these new developments is that the compound used to control the atherosclerosis is a widely available, man-made compound


http://www.thedailybeast.com/articles/2 ... sease.html

hanelyp
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Re: Factor X have we finally found the fountain of Youth?

Post by hanelyp »

And what are the side effects of this latest miracle drug?
The daylight is uncomfortably bright for eyes so long in the dark.

williatw
Posts: 1912
Joined: Mon Oct 12, 2009 7:15 pm
Location: Ohio

Re: Factor X have we finally found the fountain of Youth?

Post by williatw »

hanelyp wrote:And what are the side effects of this latest miracle drug?
From the posted link:
“It’s always very important when a new mechanism for treating high cholesterol and heart disease comes about,” McEvoy said. “This pathway and new treatment are very exciting in that regard. However, the next step for these researchers will be making sure there are no side effects of the drug that are harmful to humans.”
Chatterjee said that the actual development of the drug is about five years away. He put its science in simple terms. “Imagine you have clogged up plumbing due to debris,” Chatterjee said. “Similar clogging in our blood vessels occurs due to fat and cholesterol building up over time. Our drug, we hope, will prevent [or] delay the rise in cholesterol and fat and thus prevent thickening/hardening of the blood vessel. This is like the use of Drano to clean up our plumbing at home.”

paperburn1
Posts: 2484
Joined: Fri Jun 19, 2009 5:53 am
Location: Third rock from the sun.

Re: Factor X have we finally found the fountain of Youth?

Post by paperburn1 »

I am going to have to be nicer to the grand kids
http://www.nytimes.com/2014/05/05/scien ... .html?_r=0
I am not a nuclear physicist, but play one on the internet.

choff
Posts: 2447
Joined: Thu Nov 08, 2007 5:02 am
Location: Vancouver, Canada

Re: Factor X have we finally found the fountain of Youth?

Post by choff »

Seems Count Dracula was on to something, probably the Chinese Communist leaders as well.

http://www.telegraph.co.uk/science/scie ... -find.html

Added this just for fun, always wondered about the royals.

http://chrisspivey.org/count-dracula-an ... backwards/

Wonder if this is part of Googles plan for us.
CHoff

mvanwink5
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Re: Factor X have we finally found the fountain of Youth?

Post by mvanwink5 »

OMG, CHoff, I have been sheltered. LOL. What the NSA must have...It's better than Area 51 secrets. :lol:
Counting the days to commercial fusion. It is not that long now.

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